I am pleased with the comprehensive nature of the report. I offer two specific technical comments.
2. The issue of normalizing partial day samples to 24-h samples is briefly addressed in lines 3632-3644). Although volume and mass normalization are addressed much later in the report (lines 4334-4346), the only method of normalization mentioned in this initial discussion is creatinine concentration, which could possibly be interpreted as a specifically preferred method. This discussion should be expanded. Other methods that have been used include time (i.e., length of actual sampling interval), volume, and specific gravity. Limiting the discussion to creatinine implies unwarranted confidence in that method. Studies by Jackson (1966), Kim (1995), Boeniger et al. (1993), and Graul and Stanley (1982) have suggested that creatinine and specific gravity normalization do not provide improved confidence over normalization by time or volume, and creatinine and specific gravity can pose additional measurements (and cost) beyond those commonly performed. (Full citations provided on request or can be found in Section 2.10 of Methods and Models of the Hanford Internal Dosimetry Program, available at http://www.pnl.gov/main/publications/external/technical_reports/PNNL-15614rev1.pdf )